1 May 2026Drugs for external use and antiseptics
Clotrimazole, vaginal tablet
Clotrimazole vaginal-tablet guidance for vaginal candidiasis, including single-dose administration and pregnancy precautions.
This guide page is for structured reference only and does not replace a clinician, pharmacist, or emergency review. Dose choice, route choice, interactions, and safety decisions still need professional judgment.
Therapeutic action
Antifungal.
Indications
Vaginal candidiasis.
Forms and strengths, route of administration
500 mg vaginal tablet, with applicator.
Dose and duration
- Adult: one vaginal tablet single dose, at bedtime, preferably lying down.
- Place the tablet on the applicator.
- Insert the applicator high into the vagina.
- Push the plunger then remove the applicator.
Contra-indications, adverse effects, precautions
- May cause local irritation and allergic reactions.
- Inform patients that the oil-based vaginal tablet may damage the latex in condoms and diaphragms and reduce their effectiveness.
- Pregnancy: no contra-indication (do not use the applicator to avoid damage to the cervix).
- Breast-feeding: no contra-indication.
- Also comes in 100 mg vaginal tablets to be used once daily at bedtime for 6 days.
- Do not interrupt treatment during menstruation.
- Clean the applicator with water after each use.
Source
MSF Essential drugs practical guidelines (January 2026)
This page reproduces the structured reference information for this batch while leaving out the Storage and Remarks sections.
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