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1 May 2026Potentially dangerous, obsolete, or ineffective

Artesunate Oral: Dosing and Precautions

Oral artesunate guidance for malaria treatment only when used in co-formulated combinations with another antimalarial.

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Artesunate oralAS oral
Prescription under medical supervision

Source reviewed

source date listed on the source page

Guide category

Potentially dangerous, obsolete, or ineffective

Safety boundary

Prescription medicine information for clinician-guided use.

Kenza Health Hub presents this medicine page as structured health education. Check dose, route, interactions, pregnancy or breast-feeding considerations, and local protocol with a qualified clinician or pharmacist. Read our medical editorial policy.

This guide page is for structured reference only and does not replace a clinician, pharmacist, or emergency review. Dose choice, route choice, interactions, and safety decisions still need professional judgment.

Use restrictions

Oral artesunate must always be administered in combination with another antimalarial in co-formulated tablets: artesunate/amodiaquine or artesunate/mefloquine.

Therapeutic action

Antimalarial.

Indications

  • Treatment of uncomplicated falciparum malaria, in combination with another antimalarial.
  • Treatment of uncomplicated malaria due to other Plasmodium species, in combination with another antimalarial, when chloroquine cannot be used.
  • Completion treatment following parenteral therapy for severe malaria, in combination with another antimalarial.

Forms and strengths

50 mg tablet.

Dosage and duration

Child and adult: 4 mg/kg once daily for 3 days in combination with another antimalarial.

Contra-indications, adverse effects, precautions

  • May cause gastrointestinal disturbances and dizziness.
  • Pregnancy: no contra-indication.
  • Breast-feeding: no contra-indication.

Source

MSF Essential drugs practical guidelines (January 2026)

This page combines source-derived medicine reference sections with Kenza editorial context, while leaving out the Storage and Remarks sections from the source batch.

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