Tramadol Oral: Dosing and Safety
Tramadol guidance for short-term moderate pain treatment, with dependence and seizure precautions.
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Source reviewed
October 2024
Guide category
Oral drugs
Safety boundary
Prescription medicine information for clinician-guided use.
Kenza Health Hub presents this medicine page as structured health education. Check dose, route, interactions, pregnancy or breast-feeding considerations, and local protocol with a qualified clinician or pharmacist. Read our medical editorial policy.
Therapeutic action
Opioid analgesic.
Indications
Moderate pain, alone or in combination with a non-opioid analgesic.
Forms and strengths
- 50 mg capsule.
- 100 mg/ml oral solution with 1 drop equal to 2.5 mg.
Dose
Use for short term treatment because of the risk of dependence and tolerance.
Due to the numerous and potentially severe adverse effects of tramadol, patients should be kept under close surveillance.
- Child over 12 years and adult: 50 to 100 mg every 4 to 6 hours, maximum 400 mg daily.
Duration
According to clinical evolution; as short as possible. In the event of prolonged treatment, do not stop abruptly and reduce doses progressively.
Contra-indications, adverse effects, precautions
- Do not administer in the event of severe respiratory depression and to patients at risk of seizures such as those with epilepsy, head injury, or meningitis.
- May cause dizziness, nausea, vomiting, drowsiness, dry mouth, sweating, and rarely allergic reactions, seizures, confusion, withdrawal symptoms, and respiratory depression in overdose.
- Do not combine with opioid analgesics, including codeine.
Source
MSF Essential drugs practical guidelines (January 2026)
This page combines source-derived medicine reference sections with Kenza editorial context, while leaving out the Storage and Remarks sections from the source batch.
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