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1 May 2026Oral drugsSource update: October 2024

Tramadol oral

Tramadol guidance for short-term moderate pain treatment, with dependence and seizure precautions.

Prescription under medical supervision
This guide page is for structured reference only and does not replace a clinician, pharmacist, or emergency review. Dose choice, route choice, interactions, and safety decisions still need professional judgment.

Therapeutic action

Opioid analgesic.

Indications

Moderate pain, alone or in combination with a non-opioid analgesic.

Forms and strengths

  • 50 mg capsule.
  • 100 mg/ml oral solution with 1 drop equal to 2.5 mg.

Dose

Use for short term treatment because of the risk of dependence and tolerance.

Due to the numerous and potentially severe adverse effects of tramadol, patients should be kept under close surveillance.

  • Child over 12 years and adult: 50 to 100 mg every 4 to 6 hours, maximum 400 mg daily.

Duration

According to clinical evolution; as short as possible. In the event of prolonged treatment, do not stop abruptly and reduce doses progressively.

Contra-indications, adverse effects, precautions

  • Do not administer in the event of severe respiratory depression and to patients at risk of seizures such as those with epilepsy, head injury, or meningitis.
  • May cause dizziness, nausea, vomiting, drowsiness, dry mouth, sweating, and rarely allergic reactions, seizures, confusion, withdrawal symptoms, and respiratory depression in overdose.
  • Do not combine with opioid analgesics, including codeine.

Source

MSF Essential drugs practical guidelines (January 2026)

This page reproduces the structured reference information for this batch while leaving out the Storage and Remarks sections.

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