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1 May 2026Oral drugsSource update: October 2024

Paracetamol = Acetaminophen oral

Paracetamol guidance for mild pain and fever with age-based dosing and overdose precautions.

This guide page is for structured reference only and does not replace a clinician, pharmacist, or emergency review. Dose choice, route choice, interactions, and safety decisions still need professional judgment.

Therapeutic action

  • Analgesic, antipyretic.

Indications

  • Mild pain.
  • Fever.

Forms and strengths

  • 100 mg and 500 mg tablets.
  • 100 mg dispersible tablet.
  • 120 mg/5 ml oral suspension.

Dose

  • Child under 1 month: 10 mg/kg 3 or 4 times daily, maximum 40 mg/kg daily.
  • Child 1 month and over: 15 mg/kg 3 or 4 times daily, maximum 60 mg/kg daily.
  • Adult: 1 g 3 or 4 times daily, maximum 4 g daily.

Duration

According to clinical response.

Contra-indications, adverse effects, precautions

Do not exceed indicated doses, especially in children and older patients. Paracetamol intoxications are severe and may cause hepatic cytolysis.

  • Administer with caution to patients with hepatic impairment.
  • Reduce the dose in children with severe acute malnutrition to 10 mg/kg up to 3 times maximum per 24 hours.
  • Reduce the dose in patients with dengue with warning signs: child 10 mg/kg 3 to 4 times daily; adult 500 mg 3 to 4 times daily.
  • Pregnancy: no contra-indication.
  • Breast-feeding: no contra-indication.

Source

MSF Essential drugs practical guidelines (January 2026)

This page reproduces the structured reference information for this batch while leaving out the Storage and Remarks sections.

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