Loratadine Oral: Dosing and Precautions
Loratadine guidance for minor allergic reactions, with reduced-dose use in severe renal or hepatic impairment.
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Source reviewed
February 2024
Guide category
Oral drugs
Safety boundary
Prescription medicine information for clinician-guided use.
Kenza Health Hub presents this medicine page as structured health education. Check dose, route, interactions, pregnancy or breast-feeding considerations, and local protocol with a qualified clinician or pharmacist. Read our medical editorial policy.
Therapeutic action
H1 antihistamine.
Indications
Symptomatic treatment of minor allergic reactions such as urticaria and allergic conjunctivitis.
Forms and strengths
- 5 mg/5 ml oral solution.
- 10 mg tablet.
Dose
- Child over 2 years and under 30 kg: 5 mg (5 ml) once daily.
- Child over 30 kg and adult: 10 mg (1 tablet) once daily.
Duration
As short as possible (a few days).
Contra-indications, adverse effects, precautions
- Administer with caution and reduce the dose by giving every other day in patients with severe renal or hepatic impairment.
- May cause headache, dizziness, drowsiness, nervousness, insomnia, increased appetite, and rash.
- Monitor combination with CNS depressants and with erythromycin, fluconazole, fluoxetine, amiodarone, ritonavir, and cimetidine because loratadine concentrations may increase.
- Avoid alcohol during treatment.
- Pregnancy: avoid during the first trimester.
- Breast-feeding: no contra-indication.
Source
MSF Essential drugs practical guidelines (January 2026)
This page combines source-derived medicine reference sections with Kenza editorial context, while leaving out the Storage and Remarks sections from the source batch.
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