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1 May 2026Injectable drugs

Lidocaine Injectable: Local Anaesthesia Dosing

Lidocaine injectable guidance for local anaesthesia in minor operations and dental surgery.

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Prescription under medical supervision

Source reviewed

source date listed on the source page

Guide category

Injectable drugs

Safety boundary

Prescription medicine information for clinician-guided use.

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This guide page is for structured reference only and does not replace a clinician, pharmacist, or emergency review. Dose choice, route choice, interactions, and safety decisions still need professional judgment.

Therapeutic action

Local anaesthetic.

Indications

  • Local anaesthesia for minor operations using 1% lidocaine.
  • Dental surgery using 2% lidocaine, plain or with epinephrine.

Forms and strengths, route of administration

  • 1% solution in 20 and 50 ml vials (10 mg/ml) for SC infiltration.
  • 2% solution in 20 and 50 ml vials (20 mg/ml) for SC infiltration.

Dose

  • The volume to be injected depends on the surface area to be anaesthetised.
  • Do not exceed: child 5 mg/kg/injection.
  • Do not exceed: adult 200 mg, equal to 20 ml of lidocaine 1% or 10 ml of lidocaine 2%.

Duration

One injection, repeated if necessary. Anaesthesia is produced within 2 to 5 minutes and lasts 1 to 1.5 hours.

Contra-indications, adverse effects, precautions

  • Do not administer if known allergy to lidocaine or impaired cardiac conduction.
  • When anaesthetising the extremities, inject distally at the base, in a circle, without tourniquet and without epinephrine.
  • Do not use lidocaine for the incision of abscesses due to the risk of spreading the infection.
  • In dental surgery, epinephrine added to lidocaine prolongs anaesthesia.
  • Never use solutions with epinephrine for anaesthesia of extremities such as fingers or for penile nerve block due to the risk of ischaemia and necrosis.
  • Pregnancy and breast-feeding: no contra-indication.
  • Do not confuse with lidocaine 5% hyperbaric, which is reserved for spinal anaesthesia.
  • To simplify protocols, use lidocaine 2% with epinephrine for dental anaesthesia and lidocaine 1% without epinephrine for cutaneous anaesthesia.

Source

MSF Essential drugs practical guidelines (January 2026)

This page combines source-derived medicine reference sections with Kenza editorial context, while leaving out the Storage and Remarks sections from the source batch.

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