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1 May 2026Injectable drugs

Lidocaine = Lignocaine injectable

Lidocaine injectable guidance for local anaesthesia in minor operations and dental surgery.

Prescription under medical supervision
This guide page is for structured reference only and does not replace a clinician, pharmacist, or emergency review. Dose choice, route choice, interactions, and safety decisions still need professional judgment.

Therapeutic action

Local anaesthetic.

Indications

  • Local anaesthesia for minor operations using 1% lidocaine.
  • Dental surgery using 2% lidocaine, plain or with epinephrine.

Forms and strengths, route of administration

  • 1% solution in 20 and 50 ml vials (10 mg/ml) for SC infiltration.
  • 2% solution in 20 and 50 ml vials (20 mg/ml) for SC infiltration.

Dose

  • The volume to be injected depends on the surface area to be anaesthetised.
  • Do not exceed: child 5 mg/kg/injection.
  • Do not exceed: adult 200 mg, equal to 20 ml of lidocaine 1% or 10 ml of lidocaine 2%.

Duration

One injection, repeated if necessary. Anaesthesia is produced within 2 to 5 minutes and lasts 1 to 1.5 hours.

Contra-indications, adverse effects, precautions

  • Do not administer if known allergy to lidocaine or impaired cardiac conduction.
  • When anaesthetising the extremities, inject distally at the base, in a circle, without tourniquet and without epinephrine.
  • Do not use lidocaine for the incision of abscesses due to the risk of spreading the infection.
  • In dental surgery, epinephrine added to lidocaine prolongs anaesthesia.
  • Never use solutions with epinephrine for anaesthesia of extremities such as fingers or for penile nerve block due to the risk of ischaemia and necrosis.
  • Pregnancy and breast-feeding: no contra-indication.
  • Do not confuse with lidocaine 5% hyperbaric, which is reserved for spinal anaesthesia.
  • To simplify protocols, use lidocaine 2% with epinephrine for dental anaesthesia and lidocaine 1% without epinephrine for cutaneous anaesthesia.

Source

MSF Essential drugs practical guidelines (January 2026)

This page reproduces the structured reference information for this batch while leaving out the Storage and Remarks sections.

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