Insulin, Biphasic Injectable: Dosing and Precautions
Biphasic insulin guidance for diabetes, combining short-acting and intermediate-acting insulin for SC use only.
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Source reviewed
source date listed on the source page
Guide category
Injectable drugs
Safety boundary
Prescription medicine information for clinician-guided use.
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Therapeutic action
Pancreatic antidiabetic hormone combining short-acting and intermediate-acting insulin.
Indications
Diabetes.
Forms and strengths, route of administration
- 1000 IU vial containing 30% short-acting insulin plus 70% intermediate-acting insulin in suspension (100 IU/ml with a ratio of 30:70, 10 ml), for deep SC injection in the abdomen, thigh, buttock, or arm.
- Administer with a syringe calibrated in insulin units for U-100 insulin (100 IU/ml).
- Never administer by IV injection.
Dose
- Child and adult: one to 2 injections daily.
- Dosage must be individualized according to need and adapted in the event of physical activity, change in diet, or infection.
- See "Insulin: general information".
Contra-indications, adverse effects, precautions
- Do not administer if known allergy to protamine.
- After removing the vial from refrigeration, leave it to reach room temperature.
- Shake the vial gently before use.
- Also comes in biphasic human insulin 30/70 pens and biphasic analogue insulin 30/70 (aspart) and 25/75 (lispro) pens.
Source
MSF Essential drugs practical guidelines (January 2026)
This page combines source-derived medicine reference sections with Kenza editorial context, while leaving out the Storage and Remarks sections from the source batch.
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