Insulin, biphasic injectable

Therapeutic action

Pancreatic antidiabetic hormone combining short-acting and intermediate-acting insulin.

Indications

Diabetes.

Forms and strengths, route of administration

• 1000 IU vial containing 30% short-acting insulin plus 70% intermediate-acting insulin in suspension (100 IU/ml with a ratio of 30:70, 10 ml), for deep SC injection in the abdomen, thigh, buttock, or arm.
• Administer with a syringe calibrated in insulin units for U-100 insulin (100 IU/ml).
• Never administer by IV injection.

Dose

• Child and adult: one to 2 injections daily.
• Dosage must be individualized according to need and adapted in the event of physical activity, change in diet, or infection.
• See "Insulin: general information".

Contra-indications, adverse effects, precautions

• Do not administer if known allergy to protamine.
• After removing the vial from refrigeration, leave it to reach room temperature.
• Shake the vial gently before use.
• Also comes in biphasic human insulin 30/70 pens and biphasic analogue insulin 30/70 (aspart) and 25/75 (lispro) pens.