Hyoscine butylbromide = Butylscopolamine injectable

Therapeutic action

Antispasmodic, anticholinergic drug.

Indications

Spasms of the gastrointestinal tract and genitourinary tract.

Forms and strengths, route of administration

• 20 mg in 1 ml ampoule, 20 mg/ml, for IM, SC, or slow IV injection.

Dose

• Adult: 20 to 40 mg to be repeated if necessary, maximum 100 mg daily.

Duration

According to clinical response; no prolonged treatment.

Contra-indications, adverse effects, precautions

Do not exceed recommended doses, especially in children and older patients because of the risk of severe anticholinergic effects.

• Do not administer to patients with benign prostatic hyperplasia, urinary retention, closed-angle glaucoma, or tachycardia.
• May cause urinary retention, dryness of the mouth, constipation, blurred vision, and tachycardia.
• Administer with caution and under close supervision in the event of heart failure, coronary insufficiency, cardiac rhythm disorders, hypertension, and to patients taking other anticholinergic drugs.
• Administer with caution to patients with fever because it may affect thermoregulation.
• Pregnancy: no contra-indication; no prolonged treatment.
• Breast-feeding: no contra-indication; no prolonged treatment.