Enalapril Oral: Dosing and Precautions
Enalapril guidance for hypertension and heart failure, with renal monitoring and hyperkalaemia precautions.
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Source reviewed
source date listed on the source page
Guide category
Oral drugs
Safety boundary
Prescription medicine information for clinician-guided use.
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Therapeutic action
Antihypertensive vasodilator (ACE inhibitor).
Indications
- Hypertension.
- Heart failure.
Forms and strengths
- 5 mg and 20 mg tablets.
Dose
- Adult: start with 5 mg once daily and increase according to clinical response.
- In older patients, patients taking diuretics, and patients with renal impairment, start with a lower dose and increase cautiously.
Duration
According to clinical response.
Contra-indications, adverse effects, precautions
- Do not administer to patients with history of angioedema related to ACE inhibitors, severe hypotension, or bilateral renal artery stenosis.
- May cause dry cough, hypotension, renal impairment, hyperkalaemia, dizziness, and rarely angioedema.
- Monitor renal function and serum potassium, especially in patients with renal impairment or those taking diuretics or potassium-increasing drugs.
- Avoid or monitor combination with potassium salts, spironolactone, NSAIDs, and co-trimoxazole because hyperkalaemia risk increases.
- Pregnancy: contraindicated.
- Breast-feeding: no contra-indication.
Source
MSF Essential drugs practical guidelines (January 2026)
This page combines source-derived medicine reference sections with Kenza editorial context, while leaving out the Storage and Remarks sections from the source batch.
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