Diclofenac injectable
Injectable diclofenac guidance for short-term moderate inflammatory pain, with strict duration and pregnancy restrictions.
Therapeutic action
Non-steroidal anti-inflammatory drug (NSAID), analgesic.
Indications
Moderate pain due to inflammation such as acute sciatic neuralgia, renal colic, and postoperative pain.
Forms and strengths, route of administration
- 75 mg in 3 ml ampoule, 25 mg/ml, for deep IM injection or IV infusion.
Dose
For postoperative pain, may be administered by infusion: 75 mg over 30 to 120 minutes, to be repeated after 4 to 6 hours if necessary. Do not exceed 150 mg in 24 hours.
- Adult: 75 mg by deep IM injection, to be repeated after 6 hours if necessary.
Duration
Maximum 2 days. Change to oral treatment with an analgesic as soon as possible.
Contra-indications, adverse effects, precautions
Do not exceed the recommended duration of treatment.
- Do not administer to patients with allergy to NSAIDs, peptic ulcer, coagulation defects, haemorrhage, surgery with risk of major blood loss, severe renal, hepatic or cardiac impairment, severe malnutrition, uncorrected dehydration or hypovolaemia, asthma, or severe infection.
- May cause local reactions at the injection site, renal impairment, gastrointestinal disturbances, and allergic reactions.
- Administer with caution and carefully monitor use in older patients or patients with cardiovascular disorders.
- Do not combine with other NSAIDs, diuretics, or anticoagulants.
- Pregnancy: contraindicated.
- Breast-feeding: contraindicated.
Source
MSF Essential drugs practical guidelines (January 2026)
This page reproduces the structured reference information for this batch while leaving out the Storage and Remarks sections.
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